Neonicotinoids, a class of neuro-active insecticides

Neonicotinoids are a class of neuro-active insecticides chemically similar to nicotine.The development of this class of insecticides began with work in the 1980s by Shell and the 1990s by Bayer.The neonicotinoids were developed in large part because they show reduced toxicity compared to previously used organophosphate and carbamate insecticides.Most neonicotinoids show much lower toxicity in mammals than insects, but some breakdown products are toxic.

ChEBI: The database and ontology of Chemical Entities of Biological Interest